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Dermatology Quick Reference for Primary Care

Diagnosis, Treatment, and Referral Decisions in a Single Visit

The 30 entries with the warnings that matter most on a first shift, drawn from every chapter. Read them in the car park, then drill them as flashcards.

1Skin History in Two MinutesCh. 1
Use it when

Any new rash or skin complaint.

Common error

Skipping what the patient already applied. Steroids, antifungals, and herbal products change how a rash looks.

2Stevens-Johnson Syndrome and Toxic Epidermal NecrolysisCh. 2
Recognize

Painful dusky or target-like lesions with erosions of the eyes, mouth, or genitals, fever, and skin sloughing, usually 4 to 28 days after a new drug. Under 10% of body surface is SJS, 10% to 30% is overlap, and over 30% is TEN.

Red flags

Positive Nikolsky sign, mucosal erosions, skin pain out of proportion to the rash, fever, and rapid spread.

3Fitzpatrick Phototypes and Their LimitsCh. 3
Use it when

Estimating sunburn and skin cancer risk, or recording skin tone in the chart.

Common error

Using a high phototype to say a patient cannot sunburn or get skin cancer. Melanoma and squamous cell carcinoma occur in every skin tone, and the diagnosis is often later in darker skin.

4Shave BiopsyCh. 4
Use it when

A raised lesion that does not need sampling below the dermis, such as a seborrheic keratosis, actinic keratosis, or a likely superficial basal cell carcinoma. It is not for a lesion that might be melanoma.

Common error

Shaving a pigmented lesion that could be melanoma. A shave can cut through the base and make it impossible to measure tumor thickness.

5Potency Classes at a GlanceCh. 5
Use it when

Choosing or comparing a topical steroid.

Common error

Using a drug name alone. Betamethasone, for example, spans several classes depending on formulation.

6Tacrolimus OintmentCh. 6
Used for

Moderate to severe atopic dermatitis on the face, eyelids, and folds, and as steroid-sparing maintenance. Also used off-label for vitiligo and seborrheic dermatitis.

Safety

Boxed warning for rare cases of lymphoma and skin cancer. Long-term safety data are reassuring, but avoid it in immunocompromised patients.

7DoxycyclineCh. 7
Used for

Inflammatory acne, rosacea, purulent skin infection, and tick-borne rashes. It is strongly recommended by the AAD for acne.

Safety

Avoid in pregnancy. Do not combine with isotretinoin because both can raise brain pressure.

8Atopic Dermatitis in AdultsCh. 8
Recognize

A chronic, relapsing, itchy rash of dry, red or violaceous, scaly patches on the flexures, neck, face, and hands. Adults often have hand and eyelid involvement and thickened skin.

Red flags

Punched-out erosions suggest eczema herpeticum. Yellow crust suggests infection. New adult erythroderma suggests lymphoma.

9Acne Severity GradingCh. 9
Use it when

Choosing a starting treatment for any patient with acne.

Common error

Grading by lesion count alone. A patient with a few nodules, early scars, and low mood needs stronger therapy than the count suggests.

10Plaque PsoriasisCh. 10
Recognize

Sharply bordered red plaques with thick silvery scale on the elbows, knees, scalp, and lower back. Scraping the scale can cause pinpoint bleeding, known as the Auspitz sign, and new plaques can appear at sites of injury.

Red flags

Joint pain, a sudden spread of small plaques, pustules, or redness of the whole body.

11ImpetigoCh. 11
Recognize

Honey-colored crusted erosions around the nose and mouth in children, or flaccid blisters in the bullous form. It spreads by touch.

Red flags

Fever, rapid spread, or red or brown urine and swelling 1 to 3 weeks later, which suggest post-strep kidney disease.

12Tinea CorporisCh. 12
Recognize

One or more round or oval scaly patches with a raised red edge and central clearing, on the trunk, arms, or legs. It is itchy and spreads outward.

Red flags

Pustules or nodules at follicles suggest deeper infection. Wide, thick, fast-spreading plaques that resist terbinafine may be a resistant species. Culture them.

13Herpes LabialisCh. 13
Recognize

Tingling or burning, then grouped blisters on a red base at the lip border, which crust over in 7 to 10 days. Triggers include sun, fever, and stress.

Red flags

Lesions near the eye, or widespread lesions in eczema. See Eczema Herpeticum.

14ScabiesCh. 14
Recognize

Intense itch, worse at night, with small red papules and thread-like burrows in the finger webs, wrists, waist, genitals, and under the breasts. Family members itch too. In infants the palms, soles, and scalp are involved.

Red flags

Itch lasts 2 to 4 weeks after cure, so do not retreat for itch alone. Crusting or nursing home spread needs urgent action.

15Acute UrticariaCh. 15
Recognize

Itchy raised wheals that come and go in hours, each lasting less than 24 hours, with no bruising or scale. They last under 6 weeks.

Red flags

Lip, tongue, or throat swelling and dizziness. See Anaphylaxis in Chapter 2.

16Actinic KeratosisCh. 16
Recognize

Rough, scaly, pink or tan patches that feel like sandpaper on the face, scalp, ears, and backs of hands in sun-damaged skin. Many are felt better than seen.

Red flags

A thick, tender, rapidly growing, or bleeding lesion may already be squamous cell carcinoma. Biopsy it.

17Seborrheic KeratosisCh. 17
Recognize

Waxy, stuck-on tan to brown or black plaques with a rough, cracked surface and sharp edges, on the trunk, face, and scalp. They multiply with age and are not caused by sun.

Red flags

Bleeding, rapid growth, or a lesion that looks different from the rest. Biopsy it.

18Androgenetic Alopecia in MenCh. 18
Recognize

Receding temples and thinning of the crown, with progressive miniaturization of hairs (shorter, thinner). It begins in the late teens to 40s and has a family history.

Red flags

Sudden shedding, burning, scalp scale, or pain.

19OnychomycosisCh. 19
Recognize

A thick, yellow-white or brown, crumbly toenail, with debris under the nail and lifting from the nail bed. It begins at the free edge and spreads backward.

Red flags

Heart failure bars itraconazole. Liver disease, interacting drugs, or a dark band in the nail needs a rethink.

20Newborn Rash Quick SortCh. 20
Use it when

Any rash in the first 2 months of life. Most are benign, but a few are not.

Common error

Treating blisters in a newborn as eczema or impetigo without testing for herpes.

21Safe Topicals in PregnancyCh. 21
Use it when

Any pregnant patient with a rash who needs a topical drug.

Common error

Stopping all treatment out of fear, which leaves a severe rash untreated.

22Venous Stasis UlcerCh. 22
Recognize

A shallow, irregular, weeping ulcer on the inner ankle (the gaiter area), surrounded by brown pigment, swelling, and eczema. It is usually painless or mildly aching, and relieved by elevation.

Red flags

Rest pain, absent pulses, or an ABI under 0.5. Compression is not safe.

23Acanthosis NigricansCh. 23
Recognize

Velvety, thickened, brown to black skin in the neck, armpits, and groin folds. It is closely linked to insulin resistance and obesity.

Red flags

Sudden widespread acanthosis nigricans in an older adult may signal internal cancer, most often of the stomach.

24Medication and Exposure ReviewCh. 1
Use it when

Any rash with an unclear cause, and every widespread rash.

Common error

Forgetting supplements, topical products, and drugs stopped recently.

25DRESS SyndromeCh. 2
Recognize

Morbilliform rash with facial swelling, fever, enlarged nodes, high eosinophils, and organ involvement, usually the liver. It begins 2 to 8 weeks after starting a drug such as allopurinol, an anticonvulsant, a sulfonamide, or vancomycin.

Red flags

Rash over half the body, fever above 101°F, liver injury, kidney injury, and symptoms that flare weeks after the drug is stopped.

26Erythema in Darker SkinCh. 3
Use it when

Any inflammatory rash in brown or Black skin.

Common error

Missing early inflammation because it is not bright red. That delays treatment of cellulitis, eczema, and lupus.

27Punch BiopsyCh. 4
Use it when

Inflammatory rashes, blistering disease, hair loss, and lesions that need a full-thickness sample.

Common error

Crushing the sample with forceps. The architecture is lost and the pathologist cannot read it.

28Matching Potency to Body SiteCh. 5
Use it when

Choosing a steroid for a specific part of the body.

Common error

Using a potent steroid on the face or groin for months. The skin there absorbs more and thins fast.

29Pimecrolimus CreamCh. 6
Used for

Mild to moderate atopic dermatitis in patients 2 years and older, especially on the face and folds.

Safety

Carries the same boxed warning as tacrolimus. Do not use in immunocompromised patients or under occlusion.

30MinocyclineCh. 7
Used for

Inflammatory acne when doxycycline is not tolerated. The AAD gives a conditional recommendation.

Safety

Rare autoimmune hepatitis, lupus-like syndrome, and DRESS. Stop for joint pain, fever, or abnormal liver tests.

Each card shows when you would use an entry. Say what you would do, then check. Cards you miss come back soon; cards you know come back after longer gaps.

–new
–due
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Educational study aid, not clinical advice. Always follow your facility's protocols, the orders of the responsible provider, and current drug labeling. Ranges and doses must be checked against your local references.